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Autophagy at the Cell, Tissue and Organismal Level by Eleftherios Karanasios,Nicholas T. Ktistakis

By Eleftherios Karanasios,Nicholas T. Ktistakis

This ebook offers a professional precis of autophagy, a comparatively new yet quickly increasing box of biomedical technological know-how with vital implications in healthiness and sickness. After a historic evaluate ranging as much as the identity of autophagy genes in mammals, the authors speak about the signaling pathways that keep watch over autophagy, the mechanism of autophagosome formation and the physiological roles of autophagy in improvement, growing older, neurodegeneration, immune functionality and mobilephone differentiation. A accomplished record of beneficial antibodies for learning autophagy compiled as a group attempt is incorporated on the finish. The ebook is meant for rookies to the sector, in addition to more matured researchers searching for a condensed yet finished advent to the physiological functionality and legislation of the autophagic pathway in mammalian organisms.

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